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About This Item
CAS Number:
FEMA Number:
2336
EC Number:
MDL number:
UNSPSC Code:
12164502
NACRES:
NA.21
organoleptic:
woody; animal
grade:
FG
Kosher
natural
Kosher
natural
biological source:
Saussurea lappa Clarke
food allergen:
no known allergens
Recommended Products
biological source
Saussurea lappa Clarke
Quality Level
grade
FG
Kosher
natural
reg. compliance
EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 117
FDA 21 CFR 172.510
origin
France origin
refractive index
n20/D 1.5180 (lit.)
density
1.002 g/mL at 25 °C (lit.)
application(s)
flavors and fragrances
documentation
see Safety & Documentation for available documents
food allergen
no known allergens
organoleptic
woody; animal
Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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Occupational erythema-multiforme-like dermatitis from sensitization to costus resinoid, followed by flare-up and systemic contact dermatitis from beta-cyclocostunolide in a chemistry student.
C J Le Coz et al.
Contact dermatitis, 44(5), 310-311 (2001-05-31)
I Takanami et al.
Gan no rinsho. Japan journal of cancer clinics, 29(11), 1319-1322 (1983-09-01)
Delayed hypersensitivity skin responses to costus root oil were measured in patients with colon, stomach, breast and lung cancer and in healthy controls. Cancer patients were staged according to tumor spread. Differences were demonstrated between cancer patients and controls. Patients
S Schauder
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society, 9(3), 182-187 (1998-09-24)
Although photosensitivity after photoallergy to topical phenothiazine antihistamines is well known, there have been no previous reports of dioxopromethazine inducing this phenomenon. A housewife used 0.5% dioxopromethazine in Prothanon gel for palpebral pruritus and developed severe dermatitis of the lower
C Benezra et al.
Contact dermatitis, 15(4), 223-230 (1986-10-01)
A molecular analysis of cross-reactions in costus-sensitive patients reveals that the most active sesquiterpene lactones are the ones with the lesser number of oxygenated substituents close to the alpha-methylene-gamma-butyrolactone ring. Cross-reactions with sesquiterpene lactones with different skeletons (germacranolide and guaianolide
I Takanami et al.
Gan to kagaku ryoho. Cancer & chemotherapy, 14(7), 2276-2279 (1987-07-01)
Costus root oil is a new primary sensitizer for examination of the delayed cell-mediated immune system. Histologic findings of skin producing a positive reaction to costus root oil show accumulation of lymphoid cells. If the delayed hypersensitivity reaction caused by
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