Consumer and medical products can contain leachable chemical allergens which can cause skin sensitization. Recent efforts have been directed at the development of non-animal based tests such as in vitro cell activation assays for the identification of skin sensitizers. Prohapten
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 40(1), 10-13 (2010-10-26)
Food-associated allergies, especially to benzoates and cinnamon-related compounds, have been associated with orofacial granulomatosis and both standard and urticarial patch testing have been used to detect such allergies. Elimination diets have also been shown to be effective in some patients.
Chemical research in toxicology, 22(12), 1929-1937 (2009-11-17)
The metabolism of the potent carcinogen estragole was investigated in humans after consumption of fennel tea by analyses of its metabolites in blood plasma and urine. Stable isotope dilution assays based on LC-MS/MS detection revealed that 1'-hydroxylation of estragole happened
Journal of molecular graphics & modelling, 28(2), 196-201 (2009-08-04)
The free radical reactivity of monolignols can be explained in terms of the Fukui function and the local hard and soft acids and bases (HSAB) principle to determine the potential linkages among them for reactions involving free radicals. Our results
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 43(6), 837-866 (2005-04-07)
A toxicologic and dermatologic review of cinnamyl alcohol when used as a fragrance ingredient is presented.
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