The Journal of pharmacology and experimental therapeutics, 245(3), 928-931 (1988-06-01)
An in situ rat gut preparation was used to elucidate the mechanisms of gastrointestinal aluminum (Al) absorption. Al uptake rate at the mucosal surface was decreased by the paracellular pathway blockers kinetin (1 mM) and 2,4,6-triaminopyrimidinium (10 mM), by sodium
The Biochemical journal, 211(2), 357-361 (1983-05-01)
The Km and kcat. values for [6,6,7,7-2H]7,8(6H)-dihydropterin and 2,6-diamino-5-iminopyrimidin-4-one were determined for dihydropteridine reductase (EC 1.6.99.10) from two sources. The parameters of the pterin are of the same order as those of the most effective substrates of dihydropteridine reductase. The
Journal of the National Cancer Institute, 93(6), 436-446 (2001-03-22)
Cyclin-dependent kinase 4 (Cdk4) represents a prime target for the treatment of cancer because most human cancers are characterized by overexpression of its activating partner cyclin D1, loss of the natural Cdk4-specific inhibitor p16, or mutation(s) in Cdk4's catalytic subunit.
The effect of electrical gradients on current fluctuations and impedance recorded from Necturus gallbladder.
H Gögelein et al.
The Journal of membrane biology, 60(3), 199-209 (1981-01-01)
Revista espanola de fisiologia, 39(2), 193-196 (1983-06-01)
D-glucose diffusion in both jejunum and ileum using a perfusion system in vivo was determined. 2,4,6-triaminopyrimidine (20 mM) induced an inhibition on D-glucose diffusion of 32% in the two segments of the small intestine studied. Glucose net efflux from the
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