RNI00091

Krische Ir Catalyst: (S)-SEGPHOS, 3-nitrobenzoate ligated

Aldrich^CPR

• Synonym(s): [(S)-(-)-5,5′-Bis(diphenylphosphino)-4,4′-bi-1,3-benzodioxole][3-nitrobenzenecarboxylato][1,2,3-η-2-propenyl]iridium(III)
• Empirical Formula (Hill Notation): C₄₈H₃₆IrNO₈P₂
• Molecular Weight: 1008.97
• MDL number: MFCD27978282
• UNSPSC Code: 12352200
• PubChem Substance ID: 329824335

Properties

• form: solid
• reaction suitability: core: iridium; reagent type: catalyst
• SMILES string: [C][C][C].O=C(O[Ir]1)C2=C1C=CC([N+]([O-])=O)=C2.P(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=C6C(OCO6)=C5C7=C8C(OCO8)=CC=C7P(C9=CC=CC=C9)C%10=CC=CC=C%10
• InChI: 1S/C38H28O4P2.C7H4NO4.C3H5.Ir/c1-5-13-27(14-6-1)43(28-15-7-2-8-16-28)33-23-21-31-37(41-25-39-31)35(33)36-34(24-22-32-38(36)42-26-40-32)44(29-17-9-3-10-18-29)30-19-11-4-12-20-30;9-7(10)5-2-1-3-6(4-5)8(11)12;1-3-2;/h1-24H,25-26H2;1,3-4H,(H,9,10);3H,1-2H2;/q;;;+1/p-1
• InChI key: IQGKEOYRCUDYRW-UHFFFAOYSA-M

Description

Application

Catalyst developed by the Krische Group to affect the asymmetric carbonyl tert-prenylation (and allylation) from the alcohol or aldehyde oxidation level. Critical to the Krische group′s approach to Bryostatin 7, this catalyst is highly relevant for polyketide synthesis.

Total Synthesis of Bryostatin 7 via C–C Bond-Forming Hydrogenation

Other Notes

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Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable