N33101
Norharmane
98%
Synonym(s):
β-Carboline, 9H-Pyrido[3,4-b]indole
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About This Item
Empirical Formula (Hill Notation):
C11H8N2
CAS Number:
Molecular Weight:
168.19
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
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assay
98%
SMILES string
c1ccc2c(c1)[nH]c3cnccc23
InChI
1S/C11H8N2/c1-2-4-10-8(3-1)9-5-6-12-7-11(9)13-10/h1-7,13H
InChI key
AIFRHYZBTHREPW-UHFFFAOYSA-N
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Biochem/physiol Actions
Inhibitor of indoleamine 2,3-dioxygenase (IDO).
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M Micaela Gonzalez et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 8(8), 1139-1149 (2009-07-30)
The photochemistry of norharmane (9H-pyrido[3,4-b]indole) in acidic (pH 5.0+/-0.1) and alkaline (pH 10.0+/-0.1) aqueous solutions was studied. The photochemical reactions were monitored by TLC, UV/VIS absorption spectroscopy, high-performance liquid chromatography (HPLC), electronic ionization-mass spectrometry (EI-MS), UV-laser desorption/ionization-time of flight-mass spectrometry
Olga I Tarzi et al.
Journal of mass spectrometry : JMS, 44(2), 260-277 (2008-11-18)
The thermal stability of several commonly used crystalline matrix-assisted ultraviolet laser desorption/ionization mass spectrometry (UV-MALDI-MS) matrices, 2,5-dihydroxybenzoic acid (gentisic acid; GA), 2,4,6-trihydroxyacetophenone (THA), alpha-cyano-4-hydroxycinnamic acid (CHC), 3,5-dimethoxy-4-hydroxycinnamic acid (sinapinic acid; SA), 9H-pirido[3,4-b]indole (nor-harmane; nor-Ho), 1-methyl-9H-pirido[3,4-b]indole (harmane; Ho), perchlorate of nor-harmanonium
Rosa Busquets et al.
Molecular nutrition & food research, 53(12), 1496-1504 (2009-10-08)
Heterocyclic amines (HCAs) are potent mutagens/carcinogens to which humans are frequently exposed through the consumption of cooked meat and fish food. The effect of normal intake of HCAs and their role in the aetiology of human cancer is unknown. To
Andrés G León et al.
Journal of chromatography. A, 1192(2), 254-258 (2008-04-25)
The presence of cyclodextrins (CDs) in the mobile phase alters the chromatographic equilibria and induces a secondary chemical equilibrium associated to the chromatographic separation by HPLC. In this study the influence of the presence of CDs in the mobile phase
M Micaela Gonzalez et al.
Organic & biomolecular chemistry, 8(11), 2543-2552 (2010-05-26)
UV-A radiation (320-400 nm) induces damages to the DNA molecule and its components through photosensitized reactions. Beta-carbolines (betaCs), heterocyclic compounds widespread in biological systems, participate in several biological processes and are able to act as photosensitizers. The photosensitization of plasmidic
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