The release of 3-methylpyrazole from monolithic polymer films into aqueous media has been studied. The diffusion of the active agent decreased with increasing of the content of acetate groups in reacetylated poly(vinyl alcohols) and with increasing of the ester lengths
The release behaviour of the antimicrobially active 3(5)-methylpyrazole from matrix systems prepared from maleic anhydride copolymers as well as from copolymers of maleic esters and maleic amides was studied. Under alkaline conditions erosion is the predominant release mechanism compared to
Journal of cancer research and clinical oncology, 113(2), 145-150 (1987-01-01)
Using a hybrid ion-exchange reverse phase HPLC system, we found that F344 rat liver microsomes, in the presence of an NADPH-generating system, can metabolize methylazoxymethanol (MAM), a colon and liver carcinogen, to methanol and formic acid. This is in contrast
The diffusion of 3-methylpyrazole through a synthetic polymer matrix and the effect of the solubility of the bioactive agent in polymers on the release behaviour of polymer combinations were studied. With increasing hydrophilicity of the polymer both the diffusion and
[Toxicological evaluation of a new nitrification inhibitor and its metabolite].
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