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Key Documents

L060040

Sigma-Aldrich

Oxidizer

0.1 M, configured for MerMade

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About This Item

MDL number:
UNSPSC Code:
12352200

type

for DNA synthesis

product line

Proligo Reagents

shelf life

365 days

concentration

22.9-27.9 g/L (Iodine content, titration)

color

clear, brownish solution

compatibility

configured for MerMade

storage temp.

2-8°C

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Preparation Note

Tetrahyrofurane/Water/Pyridine/Iodine 77/2/21/2.54 (v/v/v/w)

Other Notes

Oxidizer solution, containing tetrahydrofuran (THF), pyridine, iodine and water, is applied to oxidize the chemically unstable trivalent phosphorous triester linkage formed in the coupling reaction to a stable pentavalent phosphate triester. Iodine functions as a mild oxidant and water functions as an oxygen donor.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT RE 2 Oral - STOT SE 3

target_organs

Central nervous system, Respiratory system, Thyroid

supp_hazards

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

6.1 °F

flash_point_c

-14.4 °C


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