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ALD01834

Sigma-Aldrich

3-Acetylamino-2-hydroxy-5-(trifluoromethyl)pyridine

95%

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About This Item

Empirical Formula (Hill Notation):
C8H7F3N2O2
CAS Number:
Molecular Weight:
220.15
UNSPSC Code:
12161600
NACRES:
NA.22

assay

95%

form

powder or crystals

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: C-H Activation
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
reagent type: ligand
reaction type: Cross Couplings

Application

3-Acetylamino-2-hydroxy-5-(trifluoromethyl)pyridine is a ligand developed by the Jin-Quan Yu group to affect the meta-selective C-H functionalization of phenols and anilines, including heterocyclic variants of these arenes.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Related Content

The Yu program centers around the discovery of catalytic carbon–carbon and carbon–heteroatom bond forming reactions based on C–H activation. Target transformations are selected to enable 1) the use of simple and abundant starting materials such as aliphatic acids, amines and alcohols, and 2) disconnections that drastically shorten the synthesis of a drug molecule or a major class of biologically active compounds.

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