94623

S-(1-Oxido-2-pyridyl)-N,N,N′,N′-tetramethylthiuronium tetrafluoroborate

≥95.0% (NMR)

• Synonym(s): N,N,N′,N′-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium tetrafluoroborate, S-(2-Pyridyl)-N,N,N′,N′-tetramethylthiuronium N-oxide tetrafluoroborate
• Empirical Formula (Hill Notation): C₁₀H₁₆BF₄N₃OS
• CAS Number: 255825-38-8
• Molecular Weight: 313.12
• MDL number: MFCD05664718
• UNSPSC Code: 12352005
• PubChem Substance ID: 57653625
• NACRES: NA.22

Properties

• assay: ≥95.0% (NMR)
• reaction suitability: reaction type: Coupling Reactions
• mp: 109-114 °C
• application(s): peptide synthesis
• storage temp.: −20°C
• SMILES string: F[B-](F)(F)F.CN(C)C(\Sc1cccc[n+]1[O-])=[N+](/C)C
• InChI: 1S/C10H16N3OS.BF4/c1-11(2)10(12(3)4)15-9-7-5-6-8-13(9)14;2-1(3,4)5/h5-8H,1-4H3;/q+1;-1
• InChI key: LHLFXDQURZVFLK-UHFFFAOYSA-N

Description

Application

Reagent for:
Synthesis of anticonvulsants
Solution and solid-phase peptide coupling
Conversion of carboxylic acids to Weinreb amides and N-methoxy or N-benzoxy amides
Rapid and high-yielding preparation of primary amides

Other Notes

Very reactive peptide coupling reagent[1][2]

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves