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Key Documents

901222

Sigma-Aldrich

2-{4-[(Dimethylamino)methyl]-1,2,3-triazol-1-yl}cyclohexan-1-ol

≥95%

Synonym(s):

AMTC

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About This Item

Empirical Formula (Hill Notation):
C11H20N4O
CAS Number:
Molecular Weight:
224.30
UNSPSC Code:
12352200
NACRES:
NA.22

assay

≥95%

form

powder or crystals

reaction suitability

reaction type: click chemistry

mp

81-85 °C

storage temp.

2-8°C

Application

The copper-catalyzed azide-alkyne cycloaddition reaction is a common example of a click chemistry reaction. AMTC can be used as a ligand to the copper to enhance the rate of the reaction. AMTC is water soluble similar to the copper ligand THPTA, but the ligands show different substrate specificities allowing for optimization of reaction conditions. Since AMTC is water soluble it allows for development of applications using biological molecules. After the catalysis of hydrophobic substrates in organic solvents, the aqueous solubility of the ligand allows the option of removal using an aqueous extraction.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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