900613

5-(4-(4-(Prop-2-yn-1-yloxy)benzoyl)phenoxy)pentanoic acid

≥95%

• Synonym(s): Carboxyl benzophenone alkyne, Probe building block
• Empirical Formula (Hill Notation): C₂₁H₂₀O₅
• CAS Number: 2140866-79-9
• Molecular Weight: 352.38
• UNSPSC Code: 12352106
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: ≥95%
• form: solid
• reaction suitability: reaction type: click chemistry
• storage temp.: −20°C

Description

Application

5-(4-(4-(Prop-2-yn-1-yloxy)benzoyl)phenoxy)pentanoic acid is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Other Notes

Technology Spotlight: Trifuctional Probe Building Blocks

A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319
• pcodes: P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable