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857211

Sigma-Aldrich

5-Bromo-4-chloro-3-indolyl β-D-galactopyranoside

98%

Synonym(s):

5-Bromo-4-chloro-3-indolyl β-D-galactoside, BCIG, X-gal

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About This Item

Empirical Formula (Hill Notation):
C14H15BrClNO6
CAS Number:
Molecular Weight:
408.63
Beilstein/REAXYS Number:
1402009
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

assay

98%

form

powder

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@@H](Oc2c[nH]c3ccc(Br)c(Cl)c23)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C14H15BrClNO6/c15-5-1-2-6-9(10(5)16)7(3-17-6)22-14-13(21)12(20)11(19)8(4-18)23-14/h1-3,8,11-14,17-21H,4H2/t8-,11+,12+,13-,14-/m1/s1

InChI key

OPIFSICVWOWJMJ-AEOCFKNESA-N

Application

Histochemical substrate for β-galactosidase.

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Histochemical methods for acid beta-galactosidase: technics for semipermeable membranes.
Z Lojda
Histochemie. Histochemistry. Histochimie, 37(4), 375-378 (1973-12-31)
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PloS one, 6(4), e19195-e19195 (2011-05-12)
Ischemia-reperfusion (I/R) injury associated with living donor liver transplantation impairs liver graft regeneration. Mesenchymal stem cells (MSCs) are potential cell therapeutic targets for liver disease. In this study, we demonstrate the impact of MSCs against hepatic I/R injury and hepatectomy.
Daniel Grammel et al.
Acta neuropathologica, 123(4), 601-614 (2012-02-22)
Medulloblastoma is a malignant brain tumor of childhood that comprises at least four molecularly distinct subgroups. We have previously described that cerebellar granule neuron precursors may give rise to the subgroup with a molecular fingerprint of Sonic hedgehog (Shh) signaling.
Yibing Wang et al.
PloS one, 8(3), e59195-e59195 (2013-03-26)
Our study had three objectives: to extend the plasmid-based transformation protocol to a clinical isolate of C. trachomatis belonging to the trachoma biovar, to provide "proof of principle" that it is possible to "knock out" selected plasmid genes (retaining a
Enzo R Porrello et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(1), 187-192 (2012-12-19)
We recently identified a brief time period during postnatal development when the mammalian heart retains significant regenerative potential after amputation of the ventricular apex. However, one major unresolved question is whether the neonatal mouse heart can also regenerate in response

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