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850489

Sigma-Aldrich

L-Tyrosine methyl ester hydrochloride

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About This Item

Linear Formula:
HOC6H4CH2CH(NH2)COOCH3 · HCl
CAS Number:
3417-91-2
Molecular Weight:
231.68
Beilstein/REAXYS Number:
3917353
EC Number:
222-313-3
MDL number:
MFCD00012607
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24888297
NACRES:
NA.22

form

powder

optical activity

[α]25/D +74.0°, c = 3 in pyridine

reaction suitability

reaction type: solution phase peptide synthesis

mp

192 °C (dec.) (lit.)

application(s)

peptide synthesis

storage temp.

2-8°C

SMILES string

Cl.COC(=O)[C@@H](N)Cc1ccc(O)cc1

InChI

1S/C10H13NO3.ClH/c1-14-10(13)9(11)6-7-2-4-8(12)5-3-7;/h2-5,9,12H,6,11H2,1H3;1H/t9-;/m0./s1

InChI key

VXYFARNRGZWHTJ-FVGYRXGTSA-N

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Francesca Fontana et al.
Molecules (Basel, Switzerland), 26(2) (2021-01-14)
Configurationally stable 5-aza[6]helicene (1) was envisaged as a promising scaffold for non-conventional ionic liquids (IL)s. It was prepared, purified, and separated into enantiomers by preparative HPLC on a chiral stationary phase. Enantiomerically pure quaternary salts of 1 with appropriate counterions
S Criado et al.
Photochemistry and photobiology, 68(4), 453-458 (1998-10-31)
This paper studies the dye-sensitized photooxidation of tyrosine (tyr) and tyr di- and tripeptides (tyr-tyr and tyr-tyr-tyr) mediated by singlet molecular oxygen (O2[1 delta g]) in alkaline media. Photooxidation quantum efficiencies (phi r) were obtained by determining the overall and
Rodrigo Binkowski de Andrade et al.
Molecular and cellular biochemistry, 364(1-2), 253-261 (2012-02-09)
Tyrosine levels are abnormally elevated in tissues and physiological fluids of patients with inborn errors of tyrosine catabolism, especially in tyrosinemia type II, which is caused by deficiency of tyrosine aminotransferase and provokes eyes, skin, and central nervous system disturbances.
Lin Zhang et al.
Journal of Asian natural products research, 13(3), 225-229 (2011-03-17)
Two new compounds, N-[4'-hydroxy-(E)-cinnamoyl]-l-tyrosine methyl ester (1) and methyl 4-methoxy-3-(3'-hydroxy-2'-methyl)propionyloxy-benzoate (2), were isolated from EtOAc extract of the fermentation broth of the endophytic fungus Aspergillus sp. HS-05. Their structures were elucidated by NMR, IR, UV, MS, and CD methods. Compounds
J Brtko et al.
Molecular and cellular endocrinology, 93(1), 81-86 (1993-05-01)
Various protease inhibitors (e.g. phenylmethanesulfonyl fluoride (PMSF), tosyl-phenylalanine chloromethyl ketone (TosPheCH2Cl)) and substrates (e.g., tosyl-arginine methyl ester (TosArgOMe), tryptophan methyl ester (TrpOMe)) inhibit the binding of adrenal and sex steroids to their cognate receptors (Hubbard and Kalimi (1985) Mol. Cell.
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