804436

Potassium 6-chloro-2-isonicotinoyltrifluoroborate

• Empirical Formula (Hill Notation): C₆H₃BClF₃KNO
• CAS Number: 1622923-55-0
• Molecular Weight: 247.45
• UNSPSC Code: 12352103
• NACRES: NA.22

Properties

• form: powder
• mp: 203-208 °C

Description

General description

Potassium 6-chloro-2-isonicotinoyltrifluoroborate belongs to the class of compounds known as potassium acyltrifluroborates (KATs). This trifluoroborate salt is stable and does not undergo trimerization.

Application

Potassium acyltrifluroborates (KATs) are bench, air and moisture stable reagents for rapid, chemoselective amide bond formations with hydroxylamines. These amide bond forming reactions proceed under aqueous conditions, without the need for coupling reagents or protecting groups. This product was introduced in collaboration with the Bode Research Group.

Other Notes

Rapid Ligations with Equimolar Reactants in Water with the Potassium Acyltrifluoroborate (KAT) Amide Formation
Amide-Forming Ligation of Acyltrifluoroborates and Hydroxylamines in Water
Synthesis of Chemically and Configurationally Stable Monofluoro Acylboronates: Effect of Ligand Structure on their Formation, Properties, and Reactivities

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P280 - P304 + P340 + P312 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable