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Key Documents

802174

Sigma-Aldrich

Poly(L-lactide) 4-cyano-4-[(dodecylsulfanylthiocarbonyl)sulfanyl]pentonate

average Mn 18,000, PDI ≤1.2

Synonym(s):

PLA RAFT, PLA thiocarbonyl, PLLA RAFT

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About This Item

Linear Formula:
C19H35NOS3(C3H4O2)n
UNSPSC Code:
12162002

form

powder

mol wt

average Mn 18,000

PDI

≤1.2

storage temp.

2-8°C

Application

The Poly(L-lactide) is a biodegradable polymer that contains RAFT agent functionality. The benzodithioate moiety is well suited to polymerize methacrylates and methacrylamides. PLA is commonly used in several applications, including Drug Delivery, nanoparticle surface modification,[1] end-group functionalization,[2] macroinitiator or block precursor.[3]

Legal Information

Sold for research purposes only: See sigma-aldrich.com/raftlicense. Patents: WO98/01478; WO99/311444.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Synthesis of Shape Amphiphiles Based on Functional Polyhedral Oligomeric Silsesquioxane End-Capped Poly(L-Lactide) with Diverse Head Surface Chemistry
Zhang W B, et al.
Macromolecules, 44(8), 2589-2596 (2011)
Poly(lactide)-block-Poly(HEMA) Block Copolymers: An Orthogonal One-Pot Combination of ROP and ATRP, Using a Bifunctional Initiator
Wolf F F, et al.
Macromolecules, 42(15), 5622-5628 (2009)
Preparation of Protein-Loaded Poly(L-Lactide) Microspheres by Solution-Enhanced Dispersion by Supercritical CO2
Chen A Z, et al.
Journal of Biomimetics, Biomaterials, and Tissue Engineering, 11, 93-100 (2011)

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