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802107

Sigma-Aldrich

Poly(N-isopropyl acrylamide), amine terminated

end functionalized by RAFT, PDI ≤1.3, Mn 5,000

Synonym(s):

NIPAM polymer, PNIPAM-NH2, functionalized polyNIPAM, functionalized polyacrylamide, polyacrylamide

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About This Item

Linear Formula:
H(C6H11NO)n(CH2)NH2
UNSPSC Code:
12162002
NACRES:
NA.23

form

powder

mol wt

Mn 5,000

PDI

≤1.3

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Application

Novel polymer for development of thermosensitive coated micro/nano materials including thermoresponsive polymeric drug delivery systems. The amine functinal group can be used to attach a variety of biomolecules to the polymer chain.

Legal Information

Sold for research purposes only: See sigma-aldrich.com/raftlicense. Patents: WO98/01478, WO99/311444.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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N-Isopropylacrylamide 97%

Sigma-Aldrich

415324

N-Isopropylacrylamide

Reversibly thermo-responsive alkyl-terminated poly(N-isopropylacrylamide) core-shell micellar structures.
Chung JE, et al.
Colloids and Surfaces. B, Biointerfaces, 9(1-2), 37-48 (1997)
Hua Wei et al.
Biomaterials, 28(1), 99-107 (2006-09-09)
A four-arm star block copolymer, comprised of a hydrophobic PMMA arm and an average of three hydrophilic poly(N-isopropylacrylamide) (PNIPAAm) arms were designed and synthesized from the molecular level. The amphiphilic star block copolymer is capable of self-assembling into micelles in

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