798215

L-Fmoc-4-fluorophenylalanine

• Synonym(s): Fmoc-Phe(4-F)-OH, N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-fluoro-L-phenylalanine, Fmoc-4-fluoro-L-phenylalanine
• Empirical Formula (Hill Notation): C₂₄H₂₀FNO₄
• CAS Number: 169243-86-1
• Molecular Weight: 405.42
• Beilstein/REAXYS Number: 8287377
• MDL number: MFCD00191197
• UNSPSC Code: 12352209
• PubChem Substance ID: 329768632
• NACRES: NA.22

Properties

• form: solid
• Quality Level: 100
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• color: white
• application(s): peptide synthesis
• functional group: Fmoc
• storage temp.: 2-8°C
• SMILES string: OC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)OCC2c3ccccc3-c4ccccc24
• InChI: 1S/C24H20FNO4/c25-16-11-9-15(10-12-16)13-22(23(27)28)26-24(29)30-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,26,29)(H,27,28)/t22-/m0/s1
• InChI key: IXUMACXMEZBPJG-QFIPXVFZSA-N

Description

Application

Phenylalanine derivative was introduced in collaboration with Yu and coworkers in reflection to a methodology reported in C-H Activation.

Other Notes

Ligand-Controlled C(sp³)–H Arylation and Olefination in Synthesis of Unnatural Chiral α–Amino

Acids

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable