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793841

Sigma-Aldrich

2,2-Difluoroacetophenone

Synonym(s):

α,α-Difluoroacetophenone, 2,2-Difluoro-1-phenylethanone, Difluoromethyl phenyl ketone

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About This Item

Empirical Formula (Hill Notation):
C8H6F2O
CAS Number:
Molecular Weight:
156.13
MDL number:
UNSPSC Code:
12352101
PubChem Substance ID:
NACRES:
NA.22

form

liquid

density

1.180±0.06 g/mL

SMILES string

FC(F)C(C1=CC=CC=C1)=O

InChI

1S/C8H6F2O/c9-8(10)7(11)6-4-2-1-3-5-6/h1-5,8H

InChI key

OLYKCPDTXVZOQF-UHFFFAOYSA-N

Application

Product was reported by Hartwig and coworkers in the one-pot synthesis of difluoromethylated arenes from aryl chlorides and bromides.


Pd-Catalyzed a-Arylation of a;a-Difluoroketones with Aryl Bromides and Chlorides. A Route to Difluoromethylarenes

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Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

158.0 °F

flash_point_c

70 °C


Certificates of Analysis (COA)

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Related Content

Professor Hartwig's research focuses on the discovery and understanding of new reactions catalyzed by transition metal complexes.

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