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779717

Sigma-Aldrich

19-Hydroxy-4-androstene-3,17-dione

≥90% (HPLC)

Synonym(s):

4-Androsten-19-ol-3,17-dione, 4-Androstene-3,17-dione-19-ol

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About This Item

Empirical Formula (Hill Notation):
C19H26O3
CAS Number:
510-64-5
Molecular Weight:
302.41
Beilstein/REAXYS Number:
2567249
EC Number:
208-116-5
MDL number:
MFCD00003616
UNSPSC Code:
12352103
PubChem Substance ID:
329768062

assay

≥90% (HPLC)

form

crystals

optical activity

[α]/D +190±5°, c = 1 in chloroform

storage temp.

−20°C

SMILES string

C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34CO)[C@@H]1CCC2=O

InChI

1S/C19H26O3/c1-18-8-7-16-14(15(18)4-5-17(18)22)3-2-12-10-13(21)6-9-19(12,16)11-20/h10,14-16,20H,2-9,11H2,1H3/t14-,15-,16-,18-,19+/m0/s1

InChI key

XGUHPTGEXRHMQQ-BGJMDTOESA-N

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Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H361

pcodes

P281

Hazard Classifications

Repr. 2

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCBR4993V
BCBJ9472V
BCBD0804
BCBD0804V

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S Ohigashi et al.
Nihon Naibunpi Gakkai zasshi, 65(8), 750-761 (1989-08-20)
To study the serum levels of 19-hydroxyandrostenedione (19-OH-A), known as an obligatory intermediate of estrogen biosynthesis and considered to be one of the hypertensinogens, a method using GC-MS with application of synthesized [7,7-d2]androstenedione (A), [7,7-d2] 19-OH-A and [9,11-d2]estrone(E1) as internal
J P Weniger et al.
Journal of steroid biochemistry, 35(3-4), 507-510 (1990-03-01)
Ovaries from 18-21-day-old foetal as well as from 2-10-day-old infantile rats were cultured in vitro in the presence of [3H]19-hydroxyandrostenedione and in the presence or absence of LH, FSH or (Bu)2 cAMP, and oestrone and oestradiol formed were determined by
H Morita et al.
Endocrine journal, 40(1), 89-97 (1993-02-01)
The present study was performed to clarify changes in plasma levels of 19-hydroxyandrostenedione (19-OH-AD), an amplifier of aldosterone and a possible hypertensinogenic steroid, during several tests for the renin-angiotensin system in 20 patients with aldosterone-producing adenoma (APA) and to determine
H Sekihara et al.
Clinical endocrinology, 39(5), 557-560 (1993-11-01)
We have reported that 19-hydroxyandrostenedione (19-OH-A-dione) functions as an amplifier of the sodium-retaining and hypertensive action of aldosterone. We therefore measured 19-hydroxyandrostenedione in hypertensive patients. We studied 53 normal male control subjects and 63 male patients with essential hypertension (48
H Miyashita et al.
Nihon Naibunpi Gakkai zasshi, 66(10), 1117-1125 (1990-10-20)
The conversion of androgen to estrogen is mediated by aromatase activity, and 19-hydroxylase and C10-19lyase are seen to be involved in C19-demethylation. The present study is to demonstrate C10-19lyase activity in adrenal tissue. Fetal bovine and pig adrenal tissue homogenates
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