All polyethylene imine polymers are hydrophilic and may contain approx. 30% hydrated water.
Application
Poly(vinyl acetate) is commonly used in biomedical applications. The end group functionality contains a cyanomethyl group; and the RAFT agent diphenylcarbamodithioate which will allow for additional polymerization to generate a diblock copolymer. This RAFT agent is well-suited for vinyl acetates and vinyl benzoate
The journal of gene medicine, 7(5), 657-663 (2004-11-16)
The relatively high transfection efficiency of polyethylenimine (PEI) vectors has been hypothesized to be due to their ability to avoid trafficking to degradative lysosomes. According to the proton sponge hypothesis, the buffering capacity of PEI leads to osmotic swelling and
Reversible addition–fragmentation chain transfer (RAFT) polymerization is rapidly moving to the forefront in construction of drug and gene delivery vehicles.
Microparticles in drug delivery: Study on controlling chitosan microparticle size and distribution, exploring encapsulation of BSA and TPP cross-linker.
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