767239
Polyester bis-MPA dendron, 32 hydroxyl, 1 amine
generation 5, 95%
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About This Item
UNSPSC Code:
12162002
NACRES:
NA.23
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description
hydroxyl surface groups
assay
95%
form
solid
mol wt
generation 5
feature
focal point amine
no. Surface Groups
32
mp
>300 °C
storage temp.
−20°C
General description
Polyester dendritic structures which are based on 2,2-bismethylolpropionic acid (bis-MPA) monomer are highly branched and can be end functionalized with a wide range of functional groups. They are widely used in biosensors, optics, adhesives and coatings. The hydroxyl and amine end surface groups increase the biocompatibility and the scaffolding ability of these dendritic polymers.†
Application
Amine dendrons can be covalently attached through conjugation to carboxyl groups, primary amines, or sulfhydryl groups. Amines can also attach to oxidized carbohydrate groups (usually aldehydes) by reductive amination.
Features and Benefits
Well-defined structure, high intrinsic drug loading capability, flexibility for tailored functionalization.[1]
Other Notes
Bis-MPA = 2,2-Bis(hydroxyl-methyl)propionic acid
Legal Information
Manufactured by Polymer Factory Sweden AB
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Biocompatible Dendritic Building Blocks for Advanced Biomedical Research
AB, P. F. S.
Material Matters, 7(3), 47-51 (2012)
Magnetic labelled horseradish peroxidase-polymer nanoparticles: A recyclable nanobiocatalyst
Khosravi, A., Vossoughi, M., Shahrokhian, S., & Alemzadeh, I.
J. Serb. Chem. Soc., 78(7), 921-931 (2013)
Omayra L Padilla De Jesús et al.
Bioconjugate chemistry, 13(3), 453-461 (2002-05-16)
High molecular weight polymers (> 20 000 Da) have been widely used as soluble drug carriers to improve drug targeting and therapeutic efficacy. Dendritic polymers are exceptional candidates for the preparation of near monodisperse drug carriers due to their well-defined
Anna Carlmark et al.
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been
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