European journal of medicinal chemistry, 178, 401-416 (2019-06-16)
This work mainly introduces the synthesis and characterization of three iridium(III) complexes [Ir(ppy)2(adppz)](PF6) (Ir-1), [Ir(bzq)2(addpz)](PF6) (Ir-2) and [Ir(piq)2(adppz)](PF6) (Ir-3). The complexes are more cytotoxic than cisplatin against tumor cell lines such as SGC-7901, A549, HeLa, Eca-109, HepG2 and BEL-7402. The
A group of luminescent dinuclear Ir(III) complexes were synthesized to study the application possibility as luminescent G-quadruplex (G4) sensors. According to the results, the dinuclear Ir(III) complexes 1-5 were assessed as selective G4 sensors. Among them, complex 5 not only
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