Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

750166

Sigma-Aldrich

Poly(N-isopropylacrylamide-co-methacrylic acid)

methacrylic acid 10 mol %, average Mn 8,000-10,000

Synonym(s):

Poly(NIPAM-co-MAA), Polyacrylamide, functionalized polyNIPAM, functionalized polyacrylamide, polyNIPAM

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
(C6H11NO)m (C4H6O2)n
CAS Number:
151954-97-1
UNSPSC Code:
12162002
NACRES:
NA.23

mol wt

average Mn 8,000-10,000

composition

methacrylic acid, 10 mol %

mp

>300 °C

InChI

1S/C6H11NO.C4H6O2/c1-4-6(8)7-5(2)3;1-3(2)4(5)6/h4-5H,1H2,2-3H3,(H,7,8);1H2,2H3,(H,5,6)

InChI key

BGJOTKHBFYMJST-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Intelligent Swelling/Collapsing copolymer that can be used as a temperature- and pH-sensitive materials.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKBH5656
MKBH5656V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

J Taillefer et al.
Journal of pharmaceutical sciences, 89(1), 52-62 (2000-02-09)
pH-responsive polymeric micelles (PM) consisting of random copolymers of N-isopropylacrylamide (NIPA), methacrylic acid (MAA), and octadecyl acrylate (ODA) were prepared and characterized. The critical aggregation concentration, as determined by a fluorescence probe technique, was approximately 10 mg/L in water and
Ester Chiessi et al.
The journal of physical chemistry. B, 114(25), 8301-8312 (2010-06-05)
Polymer microgels of poly(vinyl alcohol)/poly(methacrylate-co-N-isopropyl acrylamide) showed a thermoresponsive behavior, suitable for application in drug delivery (Biomacromolecules 2009, 10, 1589). In this work molecular dynamics (MD) methods were used to explain which structural aspects are determining for thermoresponsivity and how
O Meyer et al.
FEBS letters, 421(1), 61-64 (1998-02-14)
Stable liposomes were rendered pH-sensitive by complexation to a polymer that undergoes marked temperature- and pH-dependent water solubility changes. The N-isopropylacrylamide-methacrylic acid copolymer was prepared with or without octadecyl acrylate. At pH below the phase transition of the polymer, egg
Tomonori Hayashi et al.
The Analyst, 129(5), 421-427 (2004-04-30)
We synthesized a temperature-responsive polymer, N-(isopropylacrylamide)-methacrylic acid copolymer, to which poly-l-lysine was introduced. The synthesized polymer as well as the parent polymer showed reversible soluble-insoluble changes in response to temperature changes across the lower critical solution temperature at 32 degree
Kai Zhang et al.
Biomaterials, 25(22), 5281-5291 (2004-04-28)
This work was focused on the investigation of temperature and pH-responsive polymeric composite membranes and their permeability to proteins and peptides in response to environmental stimuli. The composite membranes were prepared from nanoparticles of poly(N-isopropylacrylamide-co-methacrylic acid) of various NIPAAm:MAA ratios
View All Related Papers

Articles

Stimuli-Responsive Materials as Intelligent Drug Delivery Systems

By altering the physicochemical properties, smart or intelligent drug delivery systems can be designed to deliver therapeutic molecules on-demand. Learn more about the application of stimuli-responsive materials in drug delivery.

Micro- and Nanofabricated Biomaterials

Biomaterials science integrates smart materials into biological research, requiring a deep understanding of biological systems.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service