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744786

Sigma-Aldrich

(2S)-N-[(1S)-1-(Hydroxydiphenylmethyl)-3-methylbutyl]-2-pyrrolidinecarboxamide

≥98.0% (HPLC)

Synonym(s):

(S)-N-((S)-1-Hydroxy-4-methyl-1,1-diphenylpentan-2-yl)pyrrolidine-2-carboxamide, N-[(1S)-1-(Hydroxydiphenylmethyl)-3-methylbutyl]-L-prolinamide

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About This Item

Empirical Formula (Hill Notation):
C23H30N2O2
CAS Number:
Molecular Weight:
366.50
Beilstein/REAXYS Number:
10473304
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22

assay

≥98.0% (HPLC)

form

powder

optical activity

[α]/D -49±2°, c = 1 in chloroform

SMILES string

CC(C)C[C@H](NC(=O)[C@@H]1CCCN1)C(O)(c2ccccc2)c3ccccc3

InChI

1S/C23H30N2O2/c1-17(2)16-21(25-22(26)20-14-9-15-24-20)23(27,18-10-5-3-6-11-18)19-12-7-4-8-13-19/h3-8,10-13,17,20-21,24,27H,9,14-16H2,1-2H3,(H,25,26)/t20-,21-/m0/s1

InChI key

PWBULUUPVDXEQS-SFTDATJTSA-N

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Monika Raj et al.
Organic letters, 8(18), 4097-4099 (2006-08-25)
We have demonstrated that a new class of l-proline-based organic compounds catalyzed the direct aldol reaction between aldehydes and acetone to provide beta-hydroxy ketones in good yields. The reaction is efficient, and 5-10 mol % of the catalyst and excellent
Direction of Kinetically versus Thermodynamically Controlled Organocatalysis and Its Application in Chemoenzymatic Synthesis
Rulli, G., et al.
Angewandte Chemie (International Edition in English), 50, 1-5 (2011)

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