737798

Fmoc-leu-bt

97%

• Synonym(s): (S)-(9H-Fluoren-9-yl)methyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-4-methyl-1-oxopentan-2-ylcarbamate, (S)-N-Fmoc-1-benzotriazolylcarbonyl-3-methylbutylamine
• Empirical Formula (Hill Notation): C₂₇H₂₆N₄O₃
• CAS Number: 1072840-99-3
• Molecular Weight: 454.52
• MDL number: MFCD12912215
• UNSPSC Code: 12352200
• PubChem Substance ID: 329765228
• NACRES: NA.26

Properties

• assay: 97%
• form: solid
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• mp: 121-126 °C
• application(s): peptide synthesis
• functional group: Fmoc
• storage temp.: 2-8°C
• SMILES string: CC(C)C[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(=O)n4nnc5ccccc45
• InChI: 1S/C27H26N4O3/c1-17(2)15-24(26(32)31-25-14-8-7-13-23(25)29-30-31)28-27(33)34-16-22-20-11-5-3-9-18(20)19-10-4-6-12-21(19)22/h3-14,17,22,24H,15-16H2,1-2H3,(H,28,33)/t24-/m0/s1
• InChI key: ZWFTXRDNFPCOSI-DEOSSOPVSA-N

Description

Application

Benzotriazole amino acids, or aminoacylbenzotriazolides, are versatile reagents for synthesizing peptides as well as their mimetics and conjugates. Benzotriazole amino acids have been used for the preparation of diverse derivatives including:

• Polypeptidal benzotriazolides[1]
• Peptidomimetics, such as aminoxypeptides[2], depsipeptides[3] and heterocyclic peptidomimetics[4]
• Tagged peptides and peptidomimetics, particularly those with fluorescent labels[5],[6]
• N, O, S, and C linked peptide conjugates[6]

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable