737747

z-ala-bt

• Synonym(s): (S)-N-Z-1-(Benzotriazolylcarbonyl)ethylamine, (S)-Benzyl 1-(1H-benzo[d][1,2,3] triazol-1-yl)-1-oxopropan-2-ylcarbamate
• Empirical Formula (Hill Notation): C₁₇H₁₆N₄O₃
• CAS Number: 820239-42-7
• Molecular Weight: 324.33
• MDL number: MFCD06762903
• UNSPSC Code: 12352200
• PubChem Substance ID: 329765226

Properties

• form: solid
• reaction suitability: reaction type: solution phase peptide synthesis
• mp: 95-100 °C
• application(s): peptide synthesis
• storage temp.: −20°C
• SMILES string: C[C@H](NC(OCC1=CC=CC=C1)=O)C(N(N=N2)C3=C2C=CC=C3)=O
• InChI: 1S/C17H16N4O3/c1-12(18-17(23)24-11-13-7-3-2-4-8-13)16(22)21-15-10-6-5-9-14(15)19-20-21/h2-10,12H,11H2,1H3,(H,18,23)/t12-/m0/s1
• InChI key: LREHLGSLFLKDDH-LBPRGKRZSA-N

Description

Application

Benzotriazole amino acids, or aminoacylbenzotriazolides, are versatile reagents for synthesizing peptides as well as their mimetics and conjugates. Benzotriazole amino acids have been used for the preparation of diverse derivatives including:

•  Polypeptidal benzotriazolides[1]
•  Peptidomimetics, such as aminoxypeptides[2], depsipeptides[3] and heterocyclic peptidomimetics[4]
•  Tagged peptides and peptidomimetics, particularly those with fluorescent labels[5],[6]
•  N, O, S, and C linked peptide conjugates[6]

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable