737739

Z-Ile-Bt

95%

• Synonym(s): (1S,2S-N-Z-1-Benzotriazolylcarbonyl-2-methylbutylamine, Benzyl (2S,3S)-1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-methyl-1-oxopentan-2-ylcarbamate
• Empirical Formula (Hill Notation): C₂₀H₂₂N₄O₃
• CAS Number: 1072442-07-9
• Molecular Weight: 366.41
• MDL number: MFCD22200498
• UNSPSC Code: 12352202
• PubChem Substance ID: 329765225
• NACRES: NA.22

Properties

• Product Name: Z-Ile-Bt, 95%
• assay: 95%
• form: solid
• mp: 77-82 °C
• application(s): peptide synthesis
• storage temp.: −20°C
• SMILES string: CC[C@H](C)[C@H](NC(=O)OCc1ccccc1)C(=O)n2nnc3ccccc23
• InChI: 1S/C20H22N4O3/c1-3-14(2)18(21-20(26)27-13-15-9-5-4-6-10-15)19(25)24-17-12-8-7-11-16(17)22-23-24/h4-12,14,18H,3,13H2,1-2H3,(H,21,26)/t14-,18-/m0/s1
• InChI key: DWJVZQUFTBRSCU-KSSFIOAISA-N

Description

Application

Benzotriazole amino acids, or aminoacylbenzotriazolides, are versatile reagents for synthesizing peptides as well as their mimetics and conjugates. Benzotriazole amino acids have been used for the preparation of diverse derivatives including:

• Polypeptidal benzotriazolides[1]
• Peptidomimetics, such as aminoxypeptides[2], depsipeptides[3] and heterocyclic peptidomimetics[4]
• Tagged peptides and peptidomimetics, particularly those with fluorescent labels[5][6]
• N, O, S, and C linked peptide conjugates[6]

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable