Product 724858, poly(N-isopropylacrylamide-co-methacrylic acid), is a random copolymer and is synthesized by a conventional radical polymerization route.
724858
Poly(N-isopropylacrylamide-co-methacrylic acid)
methacrylic acid 10 mol %, Mn 60,000
Synonym(s):
Poly(NIPAM-co-MAA), Polyacrylamide, functionalized polyNIPAM, functionalized polyacrylamide, polyNIPAM
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About This Item
Linear Formula:
(C6H11NO)m (C4H6O2)n
CAS Number:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.23
Pricing and availability is not currently available.
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form
solid
mol wt
Mn 60,000
composition
methacrylic acid, 10 mol %
mp
>300 °C
Mw/Mn
≤2.5
SMILES string
N(C(C)C)C(=O)C=C.OC(=O)C(=C)C
InChI
1S/C6H11NO.C4H6O2/c1-4-6(8)7-5(2)3;1-3(2)4(5)6/h4-5H,1H2,2-3H3,(H,7,8);1H2,2H3,(H,5,6)
InChI key
BGJOTKHBFYMJST-UHFFFAOYSA-N
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Application
Intelligent Swelling/Collapsing copolymer that can be used as a temperature- and pH-sensitive materials.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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J Taillefer et al.
Journal of pharmaceutical sciences, 89(1), 52-62 (2000-02-09)
pH-responsive polymeric micelles (PM) consisting of random copolymers of N-isopropylacrylamide (NIPA), methacrylic acid (MAA), and octadecyl acrylate (ODA) were prepared and characterized. The critical aggregation concentration, as determined by a fluorescence probe technique, was approximately 10 mg/L in water and
Ester Chiessi et al.
The journal of physical chemistry. B, 114(25), 8301-8312 (2010-06-05)
Polymer microgels of poly(vinyl alcohol)/poly(methacrylate-co-N-isopropyl acrylamide) showed a thermoresponsive behavior, suitable for application in drug delivery (Biomacromolecules 2009, 10, 1589). In this work molecular dynamics (MD) methods were used to explain which structural aspects are determining for thermoresponsivity and how
O Meyer et al.
FEBS letters, 421(1), 61-64 (1998-02-14)
Stable liposomes were rendered pH-sensitive by complexation to a polymer that undergoes marked temperature- and pH-dependent water solubility changes. The N-isopropylacrylamide-methacrylic acid copolymer was prepared with or without octadecyl acrylate. At pH below the phase transition of the polymer, egg
Tomonori Hayashi et al.
The Analyst, 129(5), 421-427 (2004-04-30)
We synthesized a temperature-responsive polymer, N-(isopropylacrylamide)-methacrylic acid copolymer, to which poly-l-lysine was introduced. The synthesized polymer as well as the parent polymer showed reversible soluble-insoluble changes in response to temperature changes across the lower critical solution temperature at 32 degree
Kai Zhang et al.
Biomaterials, 25(22), 5281-5291 (2004-04-28)
This work was focused on the investigation of temperature and pH-responsive polymeric composite membranes and their permeability to proteins and peptides in response to environmental stimuli. The composite membranes were prepared from nanoparticles of poly(N-isopropylacrylamide-co-methacrylic acid) of various NIPAAm:MAA ratios
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