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720143

Sigma-Aldrich

Potassium hydroxide on alumina

Synonym(s):

KOH on alumina

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About This Item

Empirical Formula (Hill Notation):
HKO
Molecular Weight:
56.11
MDL number:
UNSPSC Code:
12352301
PubChem Substance ID:
NACRES:
NA.22

form

powder

mp

>300 °C

SMILES string

[OH-].[K+]

InChI

1S/K.H2O/h;1H2/q+1;/p-1

InChI key

KWYUFKZDYYNOTN-UHFFFAOYSA-M

Application

Potassium hydroxide on alumina (KOH/AL2O3) can be employed as a base catalyst:
  • For the dehydrogenation of cyclic hydrocarbons (cycloolefins, cycloparaffins, and alkyl aromatics).[1]
  • To prepare pyridazine derivatives from 1,2-dicarbonyls, and hydrazine hydrate under microwave (MW) irradiation.[2]
  • In the total synthesis of natural product (-)-varitriol and (-)-3′-epi-varitriol (an isomer of (-)-varitriol) as potent antitumor agents.[3]

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1A

Storage Class

8B - Non-combustible corrosive hazardous materials

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Potassium hydroxide impregnated Alumina (KOH-Alumina) as a recyclable catalyst for the solvent-free multicomponent synthesis of highly functionalized substituted pyridazines and/or substituted pyridazin-3 (2H)-ones under microwave irradiation
Mecadon H and Myrboh B
ISRN Organic Chemistry, 2011(1), 131-136 (2011)
Gas phase base-catalyzed dehydrogenations of cyclic hydrocarbons over a KOH/Al2O3 catalyst
Neumann R and Sasson Y
J. Mol. Catal., 35(1), 131-136 (1986)
The synthesis of (-)-varitriol and (-)-3?-epi-varitriol via a Ramberg-Backlund route
McAllister GD, et al.
Tetrahedron, 63(49), 12123-12130 (2007)
Mizuki Takemoto et al.
PloS one, 10(6), e0131094-e0131094 (2015-06-27)
Channelrhodopsin (ChR) is a light-gated cation channel that responds to blue light. Since ChR can be readily expressed in specific neurons to precisely control their activities by light, it has become a powerful tool in neuroscience. Although the recently solved
Nilesh M Agalave et al.
Pain, 155(9), 1802-1813 (2014-06-24)
Extracellular high mobility group box-1 protein (HMGB1) plays important roles in the pathogenesis of nerve injury- and cancer-induced pain. However, the involvement of spinal HMGB1 in arthritis-induced pain has not been examined previously and is the focus of this study.

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