71494

Sodium diformylamide

≥97.0% (NT)

• Synonym(s): Diformylimide sodium salt
• Linear Formula: (HCO)₂NNa
• CAS Number: 18197-26-7
• Molecular Weight: 95.03
• Beilstein/REAXYS Number: 3567185
• MDL number: MFCD00145302
• UNSPSC Code: 12352111
• PubChem Substance ID: 57652305
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: ≥97.0% (NT)
• form: powder
• functional group: amine
• SMILES string: [Na+].O=C[N-]C=O
• InChI: 1S/C2H3NO2.Na/c4-1-3-2-5;/h1-2H,(H,3,4,5);/q;+1/p-1
• InChI key: QJXDSDLNUKLDBP-UHFFFAOYSA-M

Description

Application

Reactant for preparation of:

• Functionalized condensed benzazoles
• α-ketoheterocycles as inhibitors of Leishmania mexicana cysteine protease CPB
• INOS inhibitor PHA-399733 via Bucherer-Bergs hydantoin synthesis
• Antibiotic resistance (C β-lactamase AmpC ) inhibitor analogues, with improved cell permeability properties
• BINOL- and H8-BINOL-based aryl phosphites as ligands in palladium-catalyzed asymmetric allylation and amination reactions
• Precursors of αVβ3 integrin antagonists

Other Notes

Modified Gabriel reagent for the synthesis of amines; mild hydrolysis to release the amine[1][2][3]

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves