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70940

Sigma-Aldrich

(R)-(+)-1-(2-Naphthyl)ethylamine

≥99.0% (sum of enantiomers, GC)

Synonym(s):

(R)-(+)-α-Methyl-2-naphthalenemethylamine

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About This Item

Empirical Formula (Hill Notation):
C12H13N
CAS Number:
Molecular Weight:
171.24
Beilstein/REAXYS Number:
3195950
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:

assay

≥99.0% (sum of enantiomers, GC)

form

solid

optical activity

[α]20/D +21±1°, c = 1% in methanol

mp

47-50 °C

SMILES string

C[C@@H](N)c1ccc2ccccc2c1

InChI

1S/C12H13N/c1-9(13)11-7-6-10-4-2-3-5-12(10)8-11/h2-9H,13H2,1H3/t9-/m1/s1

InChI key

KHSYYLCXQKCYQX-SECBINFHSA-N

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Other Notes

Versatile chiral primary amine; studies about aldol reactions of the acetamide[1]; and reactions with the corresponding amidocuprate[2]

pictograms

Exclamation markEnvironment

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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R. Devant et al.
Chemische Berichte, 119, 2191-2191 (1986)
M G Bock et al.
Journal of medicinal chemistry, 30(10), 1853-1857 (1987-10-01)
A series of statine-containing tetrapeptides, systematically modified at the carboxy terminus with various hydrophobic aromatic groups, is described. These compounds were tested in vitro for their ability to inhibit porcine, human plasma, and purified human kidney renins. These analogues help

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