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699802

Sigma-Aldrich

Poly(ethylene glycol)methyl ether acetylene

average Mn 2,000

Synonym(s):

Poly(ethylene glycol)methyl ether, 4-pentynoate terminated, mPEG mono(4-pentynoate) terminated, mPEG mono-acetylene, mPEG-acetylene

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About This Item

Linear Formula:
CH3(OCH2CH2)n-OC(O)CH2CH2CCH
UNSPSC Code:
12162002
NACRES:
NA.23

form

solid

mol wt

average Mn 2,000

reaction suitability

reagent type: chemical modification reagent
reaction type: click chemistry

mp

50-52 °C

Mw/Mn

<1.1

Ω-end

alkyne

α-end

methoxy

polymer architecture

shape: linear
functionality: monofunctional

storage temp.

2-8°C

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

>230.0 °F

flash_point_c

> 110 °C

ppe

Eyeshields, Gloves, type N95 (US)

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Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

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