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684414

Sigma-Aldrich

Boc-L-alanine (2S)-2-hydroxylpropylamide

97%

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About This Item

Empirical Formula (Hill Notation):
C11H22N2O4
Molecular Weight:
246.30
MDL number:
UNSPSC Code:
12352108
PubChem Substance ID:
NACRES:
NA.22

assay

97%

form

solid

optical activity

[α]22/D -1.0°, c = 1 in chloroform

mp

71-80 °C

SMILES string

C[C@H](O)CNC(=O)[C@H](C)NC(=O)OC(C)(C)C

InChI

1S/C11H22N2O4/c1-7(14)6-12-9(15)8(2)13-10(16)17-11(3,4)5/h7-8,14H,6H2,1-5H3,(H,12,15)(H,13,16)/t7-,8-/m0/s1

InChI key

QBYGMGDPOWAXSC-YUMQZZPRSA-N

Application

Ligand for highly selective asymmetric transfer hydrogenation of prochiral ketones.[1]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Patrik Västilä et al.
Chemical communications (Cambridge, England), (32), 4039-4041 (2005-08-11)
The direct in situ formation of highly efficient ruthenium-catalysts for the asymmetric reduction of ketones was obtained by combining chiral ligand building blocks with a ruthenium precursor.

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Novel ligands enable efficient ketone reduction for chiral building block synthesis.

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