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55520

Sigma-Aldrich

3-Hydroxymandelic acid

≥97.0% (T)

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1 G
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1 G
$349.00

About This Item

Empirical Formula (Hill Notation):
C8H8O4
CAS Number:
Molecular Weight:
168.15
Beilstein/REAXYS Number:
2365378
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

$349.00


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Quality Level

assay

≥97.0% (T)

mp

128-132 °C

functional group

carboxylic acid
hydroxyl

SMILES string

OC(C(O)=O)c1cccc(O)c1

InChI

1S/C8H8O4/c9-6-3-1-2-5(4-6)7(10)8(11)12/h1-4,7,9-10H,(H,11,12)

InChI key

OLSDAJRAVOVKLG-UHFFFAOYSA-N

General description

3-Hydroxymandelic acid is a hydroxy acid derivative. Chiral separation of 3-hydroxymandelic acid has been achieved by ligand-exchange capillary electrochromatography.[1]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Role of the charge in continuous beds in the chiral separation of hydroxy acids by ligand-exchange capillary electrochromatography.
Lecnik O, et al.
Electrophoresis, 24(17), 2983-2985 (2003)
K Gumbhir et al.
Journal of pharmaceutical and biomedical analysis, 12(7), 943-949 (1994-07-01)
An LC method for the analysis of m-hydroxymandelic acid (MHMA) and m-hydroxyphenylglycol (MHPG) and their conjugates in human plasma was developed and validated. The method for the quantitation involved extraction of acidified plasma (subject to hydrolysis with beta-glucuronidase for 120
J R Crowley et al.
Clinica chimica acta; international journal of clinical chemistry, 109(2), 125-131 (1981-01-22)
o-Hydroxymandelic acid (OHMA), m-hydroxymandelic acid (MHMA) and p-hydroxymandelic acid (PHMA) were measured in the urine of 42 normotensive and 54 hypertensive patients. Patients having high urinary MHMA levels were all found to be ingesting medications containing m-synephrine (phenylephrine). These patients
J R Crowley et al.
Biomedical mass spectrometry, 9(4), 146-152 (1982-04-01)
m-Hydroxyphenylglycol (MHPG) has been identified in mammalian urine by gas chromatography mass spectrometry selected ion monitoring. (2H0) MHPG and (2H5) MHPG were synthesized for use as authentic sample and internal standard, respectively. After acid hydrolysis or treatment with sulfatase, the
Excretion of m-hydroxymandelic acid in human urine.
B A Davis et al.
Journal of chromatography, 222(2), 271-275 (1981-02-13)

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