530646

1H-Benzimidazole-2-sulfonic acid

98%

• Empirical Formula (Hill Notation): C₇H₆N₂O₃S
• CAS Number: 40828-54-4
• Molecular Weight: 198.20
• MDL number: MFCD00100972
• UNSPSC Code: 12352100
• PubChem Substance ID: 24877765

Properties

• assay: 98%
• mp: 116-119 °C (lit.)
• SMILES string: OS(=O)(=O)c1nc2ccccc2[nH]1
• InChI: 1S/C7H6N2O3S/c10-13(11,12)7-8-5-3-1-2-4-6(5)9-7/h1-4H,(H,8,9)(H,10,11,12)
• InChI key: GWXQTTKUYBEZBP-UHFFFAOYSA-N

Description

General description

1H-Benzimidazole-2-sulfonic acid (BISA) is a glutamate racemase (GR) inhibitor. It is a promising candidate for developing antibacterial drugs. BISA can be prepared by the oxidation of 1H-benzimidazole-2-thiol using hydrogen peroxide in the presence of potassium hydroxide.

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges