47623

Fmoc-Tyr(tBu)-OH

≥98.0% (HPLC), for peptide synthesis

• Synonym(s): N-(9-Fluorenylmethoxycarbonyl)-O-tert-butyl-L-tyrosine, Fmoc-O-tert-butyl-L-tyrosine
• Empirical Formula (Hill Notation): C₂₈H₂₉NO₅
• CAS Number: 71989-38-3
• Molecular Weight: 459.53
• Beilstein/REAXYS Number: 4216652
• EC Number: 276-262-7
• MDL number: MFCD00037129
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 57651043
• NACRES: NA.26

Properties

• product name: Fmoc-Tyr(tBu)-OH, ≥98.0% (HPLC)
• assay: ≥98.0% (HPLC)
• form: powder
• optical activity: [α]20/D −29±2°, c = 1% in DMF
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• mp: 153-156 °C (lit.)
• application(s): peptide synthesis
• functional group: Fmoc
• storage temp.: 2-8°C
• SMILES string: CC(C)(C)Oc1ccc(C[C@H](NC(=O)OCC2c3ccccc3-c4ccccc24)C(O)=O)cc1
• InChI: 1S/C28H29NO5/c1-28(2,3)34-19-14-12-18(13-15-19)16-25(26(30)31)29-27(32)33-17-24-22-10-6-4-8-20(22)21-9-5-7-11-23(21)24/h4-15,24-25H,16-17H2,1-3H3,(H,29,32)(H,30,31)/t25-/m0/s1
• InChI key: JAUKCFULLJFBFN-VWLOTQADSA-N

Description

General description

Fmoc-Tyr(tBu)-OH also known as Fmoc-O-tert-butyl-L-tyrosine, is commonly used in Fmoc solid phase peptide synthesis.

Application

Fmoc-Tyr(tBu)-OH can be used to synthesize Leu-EnkephalinAmide via solid phase synthesis in water. Additionally, it can be used to synthesize amino acid derivatives such as Fmoc-Tyr-OAllyl.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)