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43116

Sigma-Aldrich

N-(Diphenylmethyl)methylamine

≥98.0% (GC)

Synonym(s):

N-Methylbenzhydrylamine

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About This Item

Empirical Formula (Hill Notation):
C14H15N
CAS Number:
Molecular Weight:
197.28
Beilstein/REAXYS Number:
2096409
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

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assay

≥98.0% (GC)

form

solid

mp

38-42 °C

functional group

amine
phenyl

SMILES string

CNC(c1ccccc1)c2ccccc2

InChI

1S/C14H15N/c1-15-14(12-8-4-2-5-9-12)13-10-6-3-7-11-13/h2-11,14-15H,1H3

InChI key

SHDMMLFAFLZUEV-UHFFFAOYSA-N

General description

N-(Diphenylmethyl)methylamine is a sterically hindered secondary amine.[1] It participates in the synthesis of cyclooctene oxide.[2]

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Prolyl-peptidyl isomerases (PPIases) are enzymes that are found in all living organisms. They form an essential part of the cellular protein folding homeostasis machinery. PPIases are associated with many important human diseases, e.g. cardiovascular disease, cancer and Alzheimer's. The development
Eun Young Kim et al.
European journal of medicinal chemistry, 136, 428-441 (2017-05-20)
KR-12-a5 is a 12-meric α-helical antimicrobial peptide (AMP) with dual antimicrobial and anti-inflammatory activities designed from human cathelicidin LL-37. We designed and synthesized a series of d-amino acid-substituted analogs of KR-12-a5 with the aim of developing novel α-helical AMPs that
He Ma et al.
ChemMedChem, 14(19), 1710-1716 (2019-08-25)
Naturally occurring constrained peptides are frequently used as scaffolds for bioactive peptide grating due to their high stability. Here, we used in silico methods to design several constrained peptides comprising a scorpion toxin scaffold, a MDM2 binding epitope, and a
N-Diphenylmethyl-2-propenamide: theoretical study of the structure and interaction with a DNA model system.
Barone G, et al.
Journal of Molecular Structure, 572(1), 113-119 (2001)

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