Archives of pharmacal research, 32(7), 1019-1028 (2009-07-31)
The present research work compares the effect of microsphere preparation technique on micromeritics and release behaviors of theophylline microspheres. Microspheres were prepared by oil-in oil (O(1)/O(2)) emulsion solvent evaporation method (ESE) using different ratios of anhydrous theophylline to cellulose acetate
The eco-friendly poly(propylene carbonate) (PPC)/cellulose acetate butyrate (CAB) blends were prepared by melt-blending in a batch mixer for the first time. PPC and CAB were partially miscible because of the drastically shifted glass transition temperatures of both PPC and CAB
Drug development and industrial pharmacy, 29(7), 795-804 (2003-08-09)
The objective of this study was to evaluate the utility of mixtures among oppositely charged dextran derivatives as constituents of a controlled release microsphere. Carboxymethyldextran (CMD) and dextran sulfate (DS) were used as polyanions, and [2-(diethylamino) ethyl] dextran (EA) and
Journal of microencapsulation, 25(1), 31-45 (2008-01-12)
The aim of this study was to develop and characterize diclofenac sodium loaded-cellulose acetate butyrate microparticles in order to obtain a controlled-release system. The influence of the type of polymer, the volume and composition of the internal phase, drug loading
International journal of pharmaceutics, 352(1-2), 81-91 (2007-12-07)
A sustained release suspension of diltiazem, a short half-life calcium channel blocker, was developed to reduce frequency of drug administration, ease of dose adjustment and improve patient compliance. In this study, the sustained release of diltiazem was obtained by complexing
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