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390674

Sigma-Aldrich

5-(Trifluoromethoxy)isatin

98%

Synonym(s):

5-(Trifluoromethoxy)indoline-2,3-dione

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About This Item

Empirical Formula (Hill Notation):
C9H4F3NO3
CAS Number:
Molecular Weight:
231.13
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

assay

98%

mp

170-172 °C (lit.)

SMILES string

FC(F)(F)Oc1ccc2NC(=O)C(=O)c2c1

InChI

1S/C9H4F3NO3/c10-9(11,12)16-4-1-2-6-5(3-4)7(14)8(15)13-6/h1-3H,(H,13,14,15)

InChI key

XHAJMVPMNOBILF-UHFFFAOYSA-N

Application

Reactant for preparation of (fluorinated-indolinonylidene)-hydrazine-carbothioamides by condensation with thiosemicarbazides
Reactant for preparation of oxindole derivatives as TAk1 kinase inhibitors
Reactant for preparation of isatin thiosemicarbazones via condensation with thiosemicarbazones as herpes simplex virus (HSV) inhibitors
Reactant for synthesis of ortho disubstituted biphenyls
Reactant for preparation of indolinon-spirothiazolidinones as selective inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B
Reactant for synthesis of 3-substituted 2-indolinone RET kinase inhibitors
Reactant for preparation of indolone acetamides as antiseizure agents

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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