Skip to Content
MilliporeSigma
All Photos(1)

Documents

388386

Sigma-Aldrich

4,4′-Methylenebis(cyclohexyl isocyanate), mixture of isomers

90%

Synonym(s):

HMDI, Hydrogenated MDI

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
CH2(C6H10NCO)2
CAS Number:
5124-30-1
Molecular Weight:
262.35
EC Number:
225-863-2
MDL number:
MFCD00015405
UNSPSC Code:
12162002
PubChem Substance ID:
24864223
NACRES:
NA.23

assay

90%

form

liquid

refractive index

n20/D 1.497 (lit.)

mp

26 °C (lit.)

density

1.066 g/mL at 25 °C (lit.)

SMILES string

O=C=NC1CCC(CC1)CC2CCC(CC2)N=C=O

InChI

1S/C15H22N2O2/c18-10-16-14-5-1-12(2-6-14)9-13-3-7-15(8-4-13)17-11-19/h12-15H,1-9H2

InChI key

KORSJDCBLAPZEQ-UHFFFAOYSA-N

General description

4,4′-Methylenebis(cyclohexyl isocyanate), mixture of isomers (HMDI) is an aromatic diisocyanate with good mechanical properties. It is light stable and is resistant to hydrolysis. It is majorly used in the synthesis of polyurethane.

Application

HMDI forms NCO linkages which can be used in the synthesis of polyurethanes for a variety of biomedical applications.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 1

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Hyperbranched polyurethane (HBPU)-urea and HBPU-imide coatings: effect of chain extender and NCO/OH ratio on their properties
Mishra AK, et al.
Progress in Organic Coatings, 74(1), 134-141 (2012)
Electrospinning of L-tyrosine polyurethanes for potential biomedical applications
Shah PN, et al.
Polymer, 50(10), 2281-2289 (2009)
Effect of different isocyanates on the properties of soy-based polyurethanes
Javni I, et al.
Journal of Applied Polymer Science, 88(13), 2912-2916 (2003)
Tzu-Wen Chuang et al.
Journal of biomedical materials research. Part A, 86(3), 648-661 (2007-11-21)
Poor compatibility between blood and metallic coronary artery stents is one reason for arterial restenosis; however, the immobilization of anticoagulant agents on the surface of the stent is a feasible method of improving stent compatibility. Heparin, a well-known anticoagulant, has
I R White et al.
Contact dermatitis, 9(4), 300-303 (1983-07-01)
Organic di-isocyanates are used widely in industry. The concomitant respiratory complications are well-known. Cutaneous problems precipitated by skin contact with these chemicals are less well recognised. Allergic contact dermatitis caused by exposure to di-cyclohexylmethane 4,4'-di-isocyanate has been demonstrated in a
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service