361887

(1S,2S)-(+)-Thiomicamine

99%

• Synonym(s): (1S,2S)-(+)-2-Amino-1-[4-(methylthio)phenyl]-1,3-propanediol
• Linear Formula: 4-(CH₃S)C₆H₄CH(OH)CH(NH₂)CH₂OH
• CAS Number: 16854-32-3
• Molecular Weight: 213.30
• EC Number: 240-878-4
• MDL number: MFCD00134212
• UNSPSC Code: 12352112
• PubChem Substance ID: 24862274
• NACRES: NA.22

Properties

• assay: 99%
• optical activity: [α]25/D +25°, c = 1 in ethanol
• mp: 151-154 °C (lit.)
• SMILES string: CSc1ccc(cc1)[C@H](O)[C@@H](N)CO
• InChI: 1S/C10H15NO2S/c1-14-8-4-2-7(3-5-8)10(13)9(11)6-12/h2-5,9-10,12-13H,6,11H2,1H3/t9-,10-/m0/s1
• InChI key: IULJJGJXIGQINK-UWVGGRQHSA-N

Description

Application

(1S,2S)-(+)-Thiomicamine can be used:

• As a starting material in the synthesis of 3,4-dihydroisoquinolinium salts, which are employed as promoters in asymmetric epoxidation and oxidation reactions.
• As a starting material in the synthesis of an α-amino acid named (3R,4R)-4-phenyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid, which is used to prepare modified peptides of biological importance.
• As a chiral base in the resolution of an angiotensin II type 2 receptor [AT₂R] antagonist named EMA401.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves