342122

1-Methyl-3-nitroguanidine

contains ~25% water

• Linear Formula: CH₃NHC(=NH)NHNO₂
• CAS Number: 4245-76-5
• Molecular Weight: 118.09
• UNSPSC Code: 12352100
• PubChem Substance ID: 24861030
• MDL number: MFCD00024167
• Form: solid

Properties

• form: solid
• Quality Segment: 100
• contains: ~25% water
• mp: 153-155 °C (lit.)
• SMILES string: CNC(=N)N[N+]([O-])=O
• InChI: 1S/C2H6N4O2/c1-4-2(3)5-6(7)8/h1H3,(H3,3,4,5)
• InChI key: XCXKNNGWSDYMMS-UHFFFAOYSA-N

Description

General description

1-Methyl-3-nitroguanidine (MNG) is formed as intermediate during the production of hydroxyl radical during 1-methyl-3-nitro-1-nitrosoguanidine (MNNG) - induced gastric cancer in the xanthine oxidase system. MNG has been referred by the U.S. Air Force Armament Laboratory for use in explosive formulations. MNG is formed during nucleophilic attack by H₂O₂ on the nitroso nitrogen of MNNG. MNG is non-carcinogenic analog of N-methyl-N′-nitro-N-nitrosoguanidine (direct-acting carcinogen).

Application

1-Methyl-3-nitroguanidine (N-methyl-N′-nitroguanidine) was used in the synthesis of clothianidin hapten.

Safety Information

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H228,H302 + H312 + H332,H315,H319,H335
• pcodes: P210 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Sol. 1 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 4.1B - Flammable solid hazardous materials
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves, type P3 (EN 143) respirator cartridges