337757

N-(Phosphonomethyl)glycine

96%, for peptide synthesis

• Synonym(s): Glyphosate
• Linear Formula: (HO)₂P(O)CH₂NHCH₂CO₂H
• CAS Number: 1071-83-6
• Molecular Weight: 169.07
• Beilstein/REAXYS Number: 2045054
• EC Number: 213-997-4
• MDL number: MFCD00055350
• UNSPSC Code: 12352209
• PubChem Substance ID: 24860496
• NACRES: NA.22

Properties

• product name: N-(Phosphonomethyl)glycine, 96%
• assay: 96%
• form: powder
• reaction suitability: reaction type: solution phase peptide synthesis
• mp: 230 °C (dec.) (lit.)
• application(s): peptide synthesis
• SMILES string: OC(=O)CNCP(O)(O)=O
• InChI: 1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)
• InChI key: XDDAORKBJWWYJS-UHFFFAOYSA-N

Description

General description

N-(Phosphonomethyl)glycine (Glyphosate) is a broad spectrum, non-selective systemic herbicide. It plays an important role in inhibiting the activity of 5-enolpyruvylshikimic acid-3-phosphate synthase, which is involved in aromatic amino acid biosynthesis. Due to its chelation property, glyphosate can form coordinate complexes with a wide range of metal ions.

Application

• Water Pollution Analysis: Campanale et al. assessed glyphosate and AMPA pesticides in river waters and sediments, providing crucial data on the environmental distribution and persistence of N-(Phosphonomethyl)glycine derivatives. This research supports efforts to monitor and regulate environmental pollutants effectively (Campanale et al., 2024).
• Public Health Studies: Urinary biomonitoring of glyphosate exposure was conducted among farmers, utilizing N-(Phosphonomethyl)glycine as a marker. This study contributes to our understanding of occupational exposure risks and supports the development of health safety guidelines (Chang et al., 2024).

Safety Information

• pictograms: GHS05,GHS07,GHS09
• signalword: Danger
• hcodes: H312,H318,H411
• pcodes: P273 - P280 - P302 + P352 + P312 - P305 + P351 + P338 - P362 + P364 - P391
• Hazard Classifications: Acute Tox. 4 Dermal - Aquatic Chronic 2 - Eye Dam. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves