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308633

Sigma-Aldrich

2-Hydroxyethyl cellulose

average Mw ~380,000

Synonym(s):

HEC

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25 G
$59.30
500 G
$148.00

About This Item

CAS Number:
9004-62-0
MDL number:
MFCD00072770
UNSPSC Code:
12162002
NACRES:
NA.23

$59.30

Available to ship onMay 01, 2025Details

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description

Viscosity:300 - 400 cps, c = 2%; Water at 25° C

Quality Level

200

form

powder

autoignition temp.

725 °F

mol wt

average Mw ~380,000

extent of labeling

1.0 mol per mol cellulose (D.S.)
2.0 mol per mol cellulose (M.S.)

mp

288-290 °C (dec.)

density

0.6 g/mL at 25 °C (lit.)

SMILES string

O1C(C(C(C(C1CO)OC)O)OCCO)OC2C(OC(C(C2O)O)OC4C(OC(C(C4O)O)C)CO)COC3OC(C(C(C3O)O)OC)CO

InChI

1S/C29H52O21/c1-10-15(34)16(35)24(13(8-33)45-10)49-28-20(39)18(37)25(50-29-26(43-5-4-30)21(40)23(42-3)12(7-32)47-29)14(48-28)9-44-27-19(38)17(36)22(41-2)11(6-31)46-27/h10-40H,4-9H2,1-3H3

InChI key

CWSZBVAUYPTXTG-UHFFFAOYSA-N

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General description

2-Hydroxyethyl cellulose (HEC) is a water soluble biopolymer that is majorly used as a thickener and an adhesive. It has water retention which also includes good film forming ability for protective covering.[1][2]
Non-ionic water soluble polymer. Aqueous solutions are pseudoplastic. Readily disperses without lumping.

Application

Thickener, protective colloid, binder, stabilizer and suspending agent.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SDBB0414
STBL2567
STBL0542
STBK6185
STBK2003

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Distribution of substituents in O-(2-hydroxyethyl) cellulose
Lindberg B, et al.
Carbohydrate Research, 170(2), 207-214 (1987)
Chemical modification of cellulose extracted from sugarcane bagasse: Preparation of hydroxyethyl cellulose
Abdel-Halim ES
Arabian Journal of Chemistry, 7(3), 362-371 (2014)
Yaman Boluk et al.
Langmuir : the ACS journal of surfaces and colloids, 28(14), 6114-6123 (2012-03-28)
The steady-state shear and linear viscoelastic deformations of semidilute suspensions of rod-shaped nanocrystalline cellulose (NCC) particles in 1.0% hydroxyethyl cellulose and carboxymethyl cellulose solutions were investigated. Addition of NCC at the onset of semidilute suspension concentration significantly altered the rheological
Ying-Chen Chen et al.
International journal of pharmaceutics, 441(1-2), 162-169 (2012-12-15)
The aim was to develop gastroretentive drug delivery systems (GRDDSs) by combining floating and swelling. GRDDS tablets formulated with hydroxyethylcellulose (HEC), chitosan (CS) and sodium bicarbonate (SB) for evaluating floating capacity (floating lag time and duration) and swelling characteristics. CS
Liangzhu Li et al.
PloS one, 7(5), e37381-e37381 (2012-05-23)
Sifuvirtide is a proven effective HIV-1 entry inhibitor and its safety profile has been established for systemic administration. The present study evaluated the potential of sifuvirtide formulated in a universal gel for topical use as a microbicide candidate for preventing
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