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307041

Sigma-Aldrich

1-Phenyl-2-pyrrolidinone

99%

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About This Item

Empirical Formula (Hill Notation):
C10H11NO
CAS Number:
4641-57-0
Molecular Weight:
161.20
EC Number:
225-069-6
MDL number:
MFCD00003192
UNSPSC Code:
12352100
PubChem Substance ID:
24858557
NACRES:
NA.22

assay

99%

form

solid

bp

123 °C/0.2 mmHg (lit.)

mp

67-69 °C (lit.)

SMILES string

O=C1CCCN1c2ccccc2

InChI

1S/C10H11NO/c12-10-7-4-8-11(10)9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2

InChI key

JMVIVASFFKKFQK-UHFFFAOYSA-N

Related Categories

General description

A novel derivative of 1-phenyl-2-pyrrolidinone, blebbistatin, inhibits non-muscle myocin II activity with high specificity.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Mark S Duxbury et al.
Biochemical and biophysical research communications, 313(4), 992-997 (2004-01-07)
Blebbistatin is a novel 1-phenyl-2-pyrrolidinone derivative capable of inhibiting non-muscle myosin II activity with a high degree of specificity. We examined the effects of blebbistatin on pancreatic adenocarcinoma cellular migration, invasion, adhesion, and spreading. Blebbistatin dose-dependently inhibited cellular migration and

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