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293407

Sigma-Aldrich

2-Quinoxalinecarboxylic acid

97%

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500 MG
$118.00

About This Item

Empirical Formula (Hill Notation):
C9H6N2O2
CAS Number:
Molecular Weight:
174.16
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

$118.00


Available to ship onApril 30, 2025Details


Request a Bulk Order

assay

97%

mp

208 °C (dec.) (lit.)

functional group

carboxylic acid

SMILES string

OC(=O)c1cnc2ccccc2n1

InChI

1S/C9H6N2O2/c12-9(13)8-5-10-6-3-1-2-4-7(6)11-8/h1-5H,(H,12,13)

InChI key

UPUZGXILYFKSGE-UHFFFAOYSA-N

General description

Linear and Freundlich adsorption isotherm coefficient of 2-quinoxalinecarboxylic acid has been evaluated[1].

Application

2-Quinoxalinecarboxylic acid has been used in the preparation of:
  • N-(2-quinoxaloyl)-α-amino acids[2]
  • bisquinoxaloyl (bisquinoxalinecarbonyl) derivatives[3]

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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D Peng et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 28(11), 1524-1533 (2011-08-11)
The feed drug additive carbadox is a suspected carcinogen and mutagen. To monitor effectively residues of carbadox in the edible tissues of food-producing animals, an indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) to detect quinoxaline-2-carboxylic acid, the marker residue of carbadox
Lingli Huang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 874(1-2), 7-14 (2008-10-08)
Cyadox (CYX) is an antimicrobial growth-promoter of the quinoxalines. It is highly effective on improving growth and feed conversion of chicken with little toxicity. For food safety concerns, HPLC-UV methods were developed for the sequential determination of CYX and its
Synthetic Approaches to Quinoxaline Antibiotics. Synthesis of Bisquinoxaloyl Derivatives1a.
Koppel HC, et al.
The Journal of Organic Chemistry, 28(4), 1119-1122 (1963)
M Rutalj et al.
Food additives and contaminants, 13(8), 879-882 (1996-11-01)
The concentration of quinoxaline-2-carboxylic acid (QCA) determined by HPLC after alkaline hydrolysis of liver and muscle of swine, ranged from < 3 ng/g to 45.3 ng/g in liver, and from < 3 ng/g to 10.8 ng/g in muscle samples. After
M J Hutchinson et al.
The Analyst, 127(3), 342-346 (2002-05-09)
A method is described for the quantitative determination of quinoxaline-2-carboxylic acid (QCA), the marker residue for the veterinary drug carbadox, in swine liver. Tissue is subjected to alkaline hydrolysis followed by liquid-liquid extraction. QCA residues are cleaned up using automated

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