286567
Mephenesin
98%
Synonym(s):
3-(2-Methylphenoxy)-1,2-propanediol
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About This Item
Linear Formula:
CH3C6H4OCH2CH(OH)CH2OH
CAS Number:
Molecular Weight:
182.22
EC Number:
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.25
Recommended Products
assay
98%
form
powder
bp
153-154 °C/4 mmHg (lit.)
mp
69-71 °C (lit.)
SMILES string
Cc1ccccc1OCC(O)CO
InChI
1S/C10H14O3/c1-8-4-2-3-5-10(8)13-7-9(12)6-11/h2-5,9,11-12H,6-7H2,1H3
InChI key
JWDYCNIAQWPBHD-UHFFFAOYSA-N
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signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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K Sakitama
Japanese journal of pharmacology, 63(3), 369-376 (1993-11-01)
The effects of centrally acting muscle relaxants on the flexor reflex mediated by group II afferent fibers (group II flexor reflex) in anesthetized intact rats and on the intrathecal noradrenaline-HCl-induced facilitation of the group II flexor reflex in anesthetized spinal
P Guinebault et al.
Journal of chromatography, 507, 221-225 (1990-05-16)
A procedure for the determination of the CNS-active muscle-relaxant mephenesin in plasma samples is described. The method involved a single-step extraction with diethyl ether followed by high-performance liquid chromatography separation and fluorimetric detection. Linearity of the detection response was observed
M A Shuker et al.
British journal of pharmacology, 111(3), 951-955 (1994-03-01)
1. Previous studies have suggested that a series of drugs modelled on part of the strychnine molecule interfere with the development of high pressure neurological syndrome (HPNS) and it was presumed that this effect was via an action on inhibitory
S Bertrand et al.
The European journal of neuroscience, 11(2), 583-592 (1999-03-03)
The in vitro newborn rat isolated brain stem/spinal cord preparation was used to study the involvement of presynaptic inhibition in the control of the synaptic locomotor drive. The recording chamber was partitioned with Vaseline walls to separate the L1-L2 locomotor
C Beltran et al.
Annales de dermatologie et de venereologie, 136(10), 709-712 (2009-10-06)
In most cases, acute generalized exanthematous pustulosis (AGEP) is a drug reaction. Even if several systemic drugs have been reported to be a causative agent, this clinical case has rarely been observed with a topical treatment. We report here a
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