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28555

Sigma-Aldrich

Chloro(3-cyanopropyl)dimethylsilane

technical, ≥90% (GC)

Synonym(s):

(3-Cyanopropyl)dimethylchlorosilane, 4-(Chlorodimethylsilyl)butyronitrile

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About This Item

Empirical Formula (Hill Notation):
C6H12ClNSi
CAS Number:
18156-15-5
Molecular Weight:
161.70
Beilstein/REAXYS Number:
2235062
EC Number:
242-039-8
MDL number:
MFCD00001969
UNSPSC Code:
12352001
PubChem Substance ID:
57648311

grade

technical

assay

≥90% (GC)

form

liquid

refractive index

n20/D 1.446

bp

230-235 °C (lit.)

density

0.990 g/mL at 20 °C (lit.)

SMILES string

C[Si](C)(Cl)CCCC#N

InChI

1S/C6H12ClNSi/c1-9(2,7)6-4-3-5-8/h3-4,6H2,1-2H3

InChI key

GPIARXZSVWTOMD-UHFFFAOYSA-N

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signalword

Danger

Hazard Classifications

Flam. Liq. 3 - Skin Corr. 1C - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

100.4 °F - closed cup

flash_point_c

38 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
BCBQ1891V
1398468V
1398468
409908/1
400959/1

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S Falipou et al.
Bioconjugate chemistry, 10(3), 346-353 (1999-05-29)
A simple protocol to fix biological species to silica-based surfaces (silica microbeads and glass slides), using a bifunctional silane reagent (3-cyanopropyl dimethyl chlorosilane), is presented. This silane reagent was used without further derivatization. This system led to strong, but not
Ryan J White et al.
Journal of the American Chemical Society, 129(38), 11766-11775 (2007-09-06)
Protein ion-channel recordings using a glass nanopore (GNP) membrane as the support structure for lipid bilayer membranes are presented. The GNP membrane is composed of a single conical-shaped nanopore embedded in a approximately 50 microm-thick glass membrane chemically modified with
Mathias Bækbo Andersen et al.
Journal of colloid and interface science, 353(1), 301-310 (2010-10-15)
We present a combined theoretical and experimental analysis of the solid-liquid interface of fused-silica nanofabricated channels with and without a hydrophilic 3-cyanopropyldimethylchlorosilane (cyanosilane) coating. We develop a model that relaxes the assumption that the surface parameters C(1), C(2), and pK(+)
Ryusuke Miyata et al.
Micromachines, 12(1) (2021-01-23)
The reconstitution of ion-channel proteins in artificially formed bilayer lipid membranes (BLMs) forms a well-defined system for the functional analysis of ion channels and screening of the effects of drugs that act on these proteins. To improve the efficiency of
Arianne Soliven et al.
Journal of chromatography. A, 1217(39), 6085-6091 (2010-08-25)
This study investigates the synthesis and chromatographic behaviour of an analytical size cyanopropyl "cyano" bonded silica monolith. Surface modification was undertaken by treating a neat silica monolith with chloro(3-cyanopropyl)dimethyl silane in dry heptane over a two day period. The resulting

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