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285536

Sigma-Aldrich

5′-Deoxy-5′-(methylthio)adenosine

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About This Item

Empirical Formula (Hill Notation):
C11H15N5O3S
CAS Number:
Molecular Weight:
297.33
Beilstein/REAXYS Number:
42420
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
Pricing and availability is not currently available.

assay

97%

form

solid

SMILES string

CSCC1OC(C(O)C1O)n2cnc3c(N)ncnc23

InChI

1S/C11H15N5O3S/c1-20-2-5-7(17)8(18)11(19-5)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)

InChI key

WUUGFSXJNOTRMR-UHFFFAOYSA-N


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Benjamin Pommerrenig et al.
The Plant cell, 23(5), 1904-1919 (2011-05-05)
The 5-methylthioadenosine (MTA) or Yang cycle is a set of reactions that recycle MTA to Met. In plants, MTA is a byproduct of polyamine, ethylene, and nicotianamine biosynthesis. Vascular transcriptome analyses revealed phloem-specific expression of the Yang cycle gene 5-METHYLTHIORIBOSE
Ivan Hemeon et al.
Analytical chemistry, 83(12), 4996-5004 (2011-05-07)
DNA (cytosine-5)-methyltransferases (DNMTs) catalyze the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the 5-position of cytosine residues and thereby silence transcription of regulated genes. DNMTs are important epigenetic targets. However, isolated DNMTs are weak catalysts and are difficult
Tobias J Erb et al.
Nature chemical biology, 8(11), 926-932 (2012-10-09)
Functional assignment of uncharacterized proteins is a challenge in the era of large-scale genome sequencing. Here, we combine in extracto NMR, proteomics and transcriptomics with a newly developed (knock-out) metabolomics platform to determine a potential physiological role for a ribulose-1,5-bisphosphate
Barbara Roe et al.
PloS one, 6(8), e23641-e23641 (2011-08-20)
Hepatitis C virus (HCV) is capable of disrupting different facets of lipid metabolism and lipids have been shown to play a crucial role in the viral life cycle. The aim of this study was to examine the effect HCV infection
Theodoros S Symeonidis et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 14(3), 563-568 (2014-11-06)
In this study, the catalytic activity of decatungstate (W10O32(4-)) supported on mesoporous TiO2 nanoparticle assemblies (DT-MTA) was compared with that of homogeneous [Bu4N]4W10O32 catalysts under mild conditions. Our experiments showed that both catalytic systems achieve exceptionally high activity and selectivity

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