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Key Documents

284130

Sigma-Aldrich

Psoralen

97%

Synonym(s):

6,7-Furanocoumarin, 7H-Furo[3,2-g]benzopyran-7-one, Ficusin, Furo[3,2-g]coumarin

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About This Item

Empirical Formula (Hill Notation):
C11H6O3
CAS Number:
Molecular Weight:
186.16
Beilstein/REAXYS Number:
152784
EC Number:
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:

assay

97%

SMILES string

O=C1Oc2cc3occc3cc2C=C1

InChI

1S/C11H6O3/c12-11-2-1-7-5-8-3-4-13-9(8)6-10(7)14-11/h1-6H

InChI key

ZCCUUQDIBDJBTK-UHFFFAOYSA-N

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Application

Photochemical reagent for the investigation of nucleic acid structure and function.

Warning

Store in dark!

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Maria Anokhina et al.
The EMBO journal, 32(21), 2804-2818 (2013-09-05)
Although U snRNAs play essential roles in splicing, little is known about the 3D arrangement of U2, U6, and U5 snRNAs and the pre-mRNA in active spliceosomes. To elucidate their relative spatial organization and dynamic rearrangement, we examined the RNA
Biochemical aspects of psoralen photochemotherapy.
A C Moor et al.
Clinics in dermatology, 14(4), 353-365 (1996-07-01)
miR-TRAP: a benchtop chemical biology strategy to identify microRNA targets.
Huricha Baigude et al.
Angewandte Chemie (International ed. in English), 51(24), 5880-5883 (2012-05-09)
Aurelio Reyes et al.
Nucleic acids research, 41(11), 5837-5850 (2013-04-19)
The observation that long tracts of RNA are associated with replicating molecules of mitochondrial DNA (mtDNA) suggests that the mitochondrial genome of mammals is copied by an unorthodox mechanism. Here we show that these RNA-containing species are present in living
Psoralen and ultraviolet a light therapy for psoriasis.
Robert S Stern
The New England journal of medicine, 357(7), 682-690 (2007-08-19)

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